Associate Professor - Hospital Practitioner

Subject: Public Health, Clinical Research and Biostatistics


1999 : Master in Public Health (University of Paris 5)
2005 : PhD in Public Health/Biostatistics (University of Paris 5)
2012 : Authorization to supervise research (Nantes University)

Illustration 'About-us'


Rasch models
Clinical Research


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Practical issues encountered while determining Minimal Clinically Important Difference in Patient-Reported Outcomes. 

Woaye-Hune P, Hardouin JB, Lehur PA, Meurette G, Vanier A.

Health Qual Life Outcomes.
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Differential Item Functioning (DIF) in composite health measurement scale: Recommendations for characterizing DIF with meaningful consequences within the Rasch model framework. 

Rouquette A, Hardouin JB, Vanhaesebrouck A, Sébille V, Coste J.

PLoS One.
2019 Apr 9;14(4):e0215073.
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Overall performance of Oort’s procedure for response shift detection: a pilot simulation study. 

Vanier A, Sébille V, Blanchin M, Guilleux A, Hardouin JB.

Qual Life Res.
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Cross-Cultural Adaptation and Psychometric Validation of the French Version of the FAMCARE-Patient (FFP-16) Questionnaire for Outpatients With Advanced-Stage Cancer. 

Chaumier F, Flament T, Lecomte T, Vegas H, Stacoffe M, Pichon E, Narciso B, Caulet M, Barbe C, Jaillais A, Carmier D, By MA, Bourdon M, Hardouin JB.

J Pain Symptom Manage. 
2020 Jul;60(1):94-100.e. Epub 2020 Feb 21.
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Power and sample size determination for group comparison of patient-reported outcomes using polytomous Rasch models. 

Hardouin JB, Blanchin M, Feddag ML, Le Néel T, Perrot B, Sébille V.

Stat Med. 
2015 Jul 20;34(16):2444-55. Epub 2015 Mar 18.
Illustration publications


Master in Modelization in Clinical Pharmacology and Epidemiology Master in Clinical Research

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