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seminar 27 may 2021
SPHERE seminar
27/05/2021 12h30

Using pooling for RT-qPCR tests

Presenter(s) : Vincent Brault (associate professor in statistics in Grenoble)

One of the challenges of the current COVID-19 pandemic is the need to test populations as widely as possible to better detect spread and evolution. However, technical problems were highlighted, such as the tension on the availability of reagents. To limit this problem, pooling methods (mixing multiple samples before testing) are regularly considered in RT-qPCR (see, for example, Gollier et Gossner (2020)).

In this talk, we will begin by explaining the principle of an RT-qPCR test and recall the definition of the false positives and negatives. We will then look at the pooling principle and how this procedure influences the results on the rate of false negatives. In particular, we will highlight the importance of knowing the distribution of viral load concentration. Therefore, we will continue on the difficulty of estimating this concentration and conclude with a few procedures that could be applied to help in this time of crisis.

Location: Tours + zoom

Contact in Nantes

Contact in Tours

visuel Sphere
SPHERE seminar
25/06/2021

SPHERE day

Twice a year, the entire SPHERE unit meets in Tours or Nantes to discuss topics at the heart of its research topics.

More information very soon

visuel Publication
SPHERE seminar
29/03/2021 12h30

Which place for shared medical decision in the context of kidney transplantation ? A research by mixed methods on the patient experience

Presenter(s) : Emmanuelle Cartron (SPHERE, nurse and coordinator of the research for paramedical professionnels in the hospital of Nantes)

The presentation will be an overview of her PhD defense and will focus on the presentation of mixed methods in research in order to discuss current and future projects with SPHERE which have both quantitative and qualitative components.

Location: Zoom
further information:

Contact in Nantes
Contact in Tours

SPHERE day
SPHERE seminar
09/12/2021

SPHERE day

Twice a year, the entire SPHERE unit meets in Tours or Nantes to discuss topics at the heart of its research topics.

SPHERE day
SPHERE seminar
30/06/2022

SPHERE day

Twice a year, the entire SPHERE unit meets in Tours or Nantes to discuss topics at the heart of its research topics.